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5LTS

Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease Mutant D118A

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
RNA-directed RNA polymerase Lpolymer20423678.22UniProt (A0A059U382)
Pfam (PF17296)
UniProt (by SIFTS) (P14240)
Lymphocytic choriomeningitis mammarenavirusProtein L
2C
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
3D
(B)
SODIUM IONnon-polymer23.01Chemie (NA)
4E
(B)
GLYCEROLnon-polymer92.11Chemie (GOL)
5F, G
(A, B)
waterwater18.0113Chemie (HOH)
Sequence modifications
A, B: 1 - 196 (UniProt: A0A059U382)
PDBExternal DatabaseDetails
Met -7-initiating methionine
Lys -6-expression tag
His -5-expression tag
His -4-expression tag
His -3-expression tag
His -2-expression tag
His -1-expression tag
His 0-expression tag
Ala 118Asp 119engineered mutation
Asp 173Asn 174conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight47356.3
Non-Polymers*Number of molecules3
Total formula weight150.5
All*Total formula weight47506.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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