5LTN

Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease complexed with DPBA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	RNA-directed RNA polymerase L	polymer	204	23722.2	2	UniProt (A0A059U381) Pfam (PF17296) UniProt (by SIFTS) (P14240)	Lymphocytic choriomeningitis mammarenavirus	Protein L
2	C, D, M, N (A, B)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
3	E, F, O, P (A, B)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
4	G (A)	2-4-DIOXO-4-PHENYLBUTANOIC ACID	non-polymer		192.2	1	Chemie (XI7)
5	H, Q (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	I, J (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	2	Chemie (PEG)
7	K, L (A)	SODIUM ION	non-polymer		23.0	2	Chemie (NA)
8	R, S (A, B)	water	water		18.0	229	Chemie (HOH)

Sequence modifications

A, B: 1 - 196 (UniProt: A0A059U381)

PDB	External Database	Details
Met -7	-	initiating methionine
Lys -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Asp 173	Asn 174	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47444.3
Non-Polymers*	Number of molecules	15
	Total formula weight	986.9
All*	Total formula weight	48431.2

*Water molecules are not included.