5LTH

Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) in complex with the dimethylamine substrate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	heme dependent oxidative N-demethylase	polymer	344	40161.6	1	UniProt (A4XXY9) Pfam (PF11927) In PDB	Pseudomonas mendocina
2	A	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	1	Chemie (HEM)
3	A	DIMETHYLAMINE	non-polymer		45.1	1	Chemie (DMN)
4	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
5	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6		water	water		18.0	267	Chemie (HOH)

Sequence modifications

A: 1 - 338 (UniProt: A4XXY9)

PDB	External Database	Details
His 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag
His 342	-	expression tag
His 343	-	expression tag
His 344	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	40161.6
Non-Polymers*	Number of molecules	4
	Total formula weight	790.7
All*	Total formula weight	40952.3

*Water molecules are not included.