5LR7
CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR567530
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Heat shock protein HSP 90-alpha | polymer | 208 | 23304.4 | 1 | UniProt (P07900) Pfam (PF13589) In PDB | Homo sapiens (Human) | Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
2 | A | ~{N}-[(9~{R})-4-(5-fluoranyl-1~{H}-benzimidazol-2-yl)-9~{H}-fluoren-9-yl]-1~{H}-pyrrolo[2,3-b]pyridine-4-carboxamide | non-polymer | 459.5 | 1 | Chemie (73J) | |||
3 | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A: 16 - 223 (UniProt: P07900)
PDB | External Database | Details |
---|---|---|
His 16 | Glu 138 | cloning artifact |
Met 17 | Val 139 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23304.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 459.5 | |
All* | Total formula weight | 23763.9 |