5LR7
CRYSTAL STRUCTURE OF HSP90 IN COMPLEX WITH SAR567530
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock protein HSP 90-alpha | polymer | 208 | 23304.4 | 1 | UniProt (P07900) Pfam (PF13589) | Homo sapiens (Human) | Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38 |
| 2 | B (A) | ~{N}-[(9~{R})-4-(5-fluoranyl-1~{H}-benzimidazol-2-yl)-9~{H}-fluoren-9-yl]-1~{H}-pyrrolo[2,3-b]pyridine-4-carboxamide | non-polymer | 459.5 | 1 | Chemie (73J) | |||
| 3 | C (A) | water | water | 18.0 | 389 | Chemie (HOH) |
Sequence modifications
A: 16 - 223 (UniProt: P07900)
| PDB | External Database | Details |
|---|---|---|
| His 16 | Glu 138 | cloning artifact |
| Met 17 | Val 139 | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23304.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 459.5 | |
| All* | Total formula weight | 23763.9 |
