5LQF

CDK1/CyclinB1/CKS2 in complex with NU6102

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Cyclin-dependent kinase 1	polymer	302	34553.9	2	UniProt (P06493) Pfam (PF00069)	Homo sapiens (Human)	CDK1,Cell division control protein 2 homolog,Cell division protein kinase 1,p34 protein kinase
2	B, E (B, E)	G2/mitotic-specific cyclin-B1	polymer	273	31369.7	2	UniProt (P14635) Pfam (PF00134) Pfam (PF02984)	Homo sapiens (Human)
3	C, F (C, F)	Cyclin-dependent kinases regulatory subunit 2	polymer	84	10290.8	2	UniProt (P33552) Pfam (PF01111)	Homo sapiens (Human)	CKS-2
4	G, H (A, D)	O6-CYCLOHEXYLMETHOXY-2-(4'-SULPHAMOYLANILINO) PURINE	non-polymer		402.5	2	Chemie (4SP)
5	I, J, K, L, M... (A, B, C, D, E...)	water	water		18.0	291	Chemie (HOH)

Sequence modifications

A, D: 1 - 297 (UniProt: P06493)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

B, E: 165 - 433 (UniProt: P14635)

PDB	External Database	Details
Gly 161	-	expression tag
Ser 162	-	expression tag
His 163	-	expression tag
Met 164	-	expression tag
Ser 167	Cys 167	conflict
Ser 238	Cys 238	conflict
Ser 350	Cys 350	conflict

C, F: 1 - 79 (UniProt: P33552)

PDB	External Database	Details
Gly -4	-	expression tag
Pro -3	-	expression tag
Leu -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	152428.8
Non-Polymers*	Number of molecules	2
	Total formula weight	804.9
All*	Total formula weight	153233.7

*Water molecules are not included.