5LQB
Complex structure of human IL2 mutant, Proleukin, with Fab fragment of NARA1 antibody
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Interleukin-2 | polymer | 132 | 15348.8 | 1 | UniProt (P60568) Pfam (PF00715) | Homo sapiens (Human) | IL-2,T-cell growth factor,TCGF |
| 2 | B (H) | anti-hIL2 FAB fragment heavy chain | polymer | 224 | 23775.5 | 1 | Mus musculus (House Mouse) | ||
| 3 | C (L) | anti-hIL2 FAB fragment light chain | polymer | 218 | 23925.2 | 1 | Mus musculus (House Mouse) | ||
| 4 | D, E, F (A, H, L) | water | water | 18.0 | 494 | Chemie (HOH) |
Sequence modifications
A: 22 - 153 (UniProt: P60568)
| PDB | External Database | Details |
|---|---|---|
| Ser 145 | Cys 145 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 63049.5 | |
| All* | Total formula weight | 63049.5 |
