5LPU
Crystal structure of Annexin A2 complexed with S100A4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Annexin A2 | polymer | 339 | 38613.9 | 2 | UniProt (P07355) Pfam (PF00191) In PDB | Homo sapiens (Human) | Annexin II,Annexin-2,Calpactin I heavy chain,Calpactin-1 heavy chain,Chromobindin-8,Lipocortin II,Placental anticoagulant protein IV,PAP-IV,Protein I,p36 |
2 | C, D | Protein S100-A4 | polymer | 104 | 12027.8 | 2 | UniProt (P26447) Pfam (PF01023) In PDB | Homo sapiens (Human) | Calvasculin,Metastasin,Placental calcium-binding protein,Protein Mts1,S100 calcium-binding protein A4 |
3 | A, B, C, D | CALCIUM ION | non-polymer | 40.1 | 14 | Chemie (CA) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
5 | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 339 (UniProt: P07355)
C, D: 1 - 101 (UniProt: P26447)
PDB | External Database | Details |
---|---|---|
Ace 1 | - | acetylation |
Glu 66 | Ala 66 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 101283.5 | |
Non-Polymers* | Number of molecules | 19 |
Total formula weight | 1021.6 | |
All* | Total formula weight | 102305.1 |