5LPK
Crystal structure of the bromodomain of human EP300 bound to the inhibitor XDM1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Histone acetyltransferase p300 | polymer | 122 | 14436.5 | 7 | UniProt (Q09472) Pfam (PF00439) In PDB | Homo sapiens (Human) | p300 HAT,E1A-associated protein p300 |
| 2 | D, E, A, F, B... | ~{N}-[(3-chlorophenyl)methyl]-4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrole-2-carboxamide | non-polymer | 318.8 | 7 | Chemie (XDM) | |||
| 3 | E, A, F, C | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | D, E, A, F, G... | 1,2-ETHANEDIOL | non-polymer | 62.1 | 19 | Chemie (EDO) | |||
| 5 | B | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 6 | water | water | 18.0 | 483 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 101055.6 | |
| Non-Polymers* | Number of molecules | 32 |
| Total formula weight | 4085.4 | |
| All* | Total formula weight | 105141.0 |
