5LPG

Structure of NUDT15 in complex with 6-thio-GMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Probable 8-oxo-dGTP diphosphatase NUDT15	polymer	164	18635.0	2	UniProt (Q9NV35) Pfam (PF00293)	Homo sapiens (Human)	8-oxo-dGTPase NUDT15,7,8-dihydro-8-oxoguanine-triphosphatase NUDT15,MutT homolog 2,MTH2,Nucleoside diphosphate-linked moiety X motif 15,Nudix motif 15
2	C, E, F, G, H (A, B)	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
3	D (A)	[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-sulfanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate	non-polymer		379.3	1	Chemie (71V)
4	I, J (A, B)	water	water		18.0	156	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	37270.0
Non-Polymers*	Number of molecules	6
	Total formula weight	500.8
All*	Total formula weight	37770.8

*Water molecules are not included.