5LOH

Kinase domain of human Greatwall

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Serine/threonine-protein kinase greatwall,Serine/threonine-protein kinase greatwall	polymer	341	38214.5	2	UniProt (Q96GX5) Pfam (PF00069)	Homo sapiens (Human)	hGWL,Microtubule-associated serine/threonine-protein kinase-like,MAST-L,hGWL,Microtubule-associated serine/threonine-protein kinase-like,MAST-L
2	C, F (A, B)	STAUROSPORINE	non-polymer		466.5	2	Chemie (STU) PubChem (5279) PubChem (44259) PubChem (451705) PubChem (5459111) PubChem (6419748) PubChem (9804568) PubChem (9937179) PubChem (71203703) PubChem (42610657) PubChem (44299148) PubChem (25322871) PubChem (28684983) PubChem (49831000) PubChem (44120114) PubChem (44537813) PubChem (46864193) PubChem (358479) PubChem (5280487) PubChem (5311103) PubChem (6711321) PubChem (9956178) PubChem (12046017) PubChem (68262703) PubChem (68306294) PubChem (73953205) PubChem (86306248) PubChem (122130844) PubChem (143163481) PubChem (143224059) PubChem (143494026) PubChem (162978898)
3	D (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL) PubChem (312)
4	E, G, H (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
5	I, J (A, B)	water	water		18.0	56	Chemie (HOH)

Sequence modifications

A, B: 1 - 735 (UniProt: Q96GX5)

PDB	External Database	Details
Gly -2	-	expression tag
Pro -1	-	expression tag
His 0	-	expression tag

A, B: 740 - 879 (UniProt: Q96GX5)

PDB	External Database	Details
Arg 736	-	linker
Thr 737	-	linker
Phe 738	-	linker
Cys 739	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76429.0
Non-Polymers*	Number of molecules	6
	Total formula weight	1154.7
All*	Total formula weight	77583.7

*Water molecules are not included.