5LOB

Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Rabphilin-3A	polymer	162	18579.3	3	UniProt (P47709) Pfam (PF00168)	Rattus norvegicus (Norway Rat)	Exophilin-1
2	D, F (D, F)	Synaptosomal-associated protein 25	polymer	100	11266.6	2	UniProt (P60881)	Rattus norvegicus (Norway Rat)	SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein,SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein
3	E, G (E, G)	Synaptosomal-associated protein 25	polymer	96	10414.7	2	UniProt (P60881)	Rattus norvegicus (Norway Rat)	SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein,SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein
4	H, I, Q, R, V... (A, B, C)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
5	AA, DA, J, K, L... (F, G, A, B, C...)	SULFATE ION	non-polymer		96.1	10	Chemie (SO4)
6	BA, CA, EA, FA, N... (F, G, A, B, C)	GLYCEROL	non-polymer		92.1	9	Chemie (GOL)

Sequence modifications

A, B, C: 536 - 680 (UniProt: P47709)

PDB	External Database	Details
His 519	-	expression tag
Met 520	-	expression tag
Ala 521	-	expression tag
Ser 522	-	expression tag
Met 523	-	expression tag
Thr 524	-	expression tag
Gly 525	-	expression tag
Gly 526	-	expression tag
Gln 527	-	expression tag
Gln 528	-	expression tag
Met 529	-	expression tag
Gly 530	-	expression tag
Arg 531	-	expression tag
Gly 532	-	expression tag
Ser 533	-	expression tag
Asp 534	-	expression tag
Phe 535	-	expression tag

D, F: -17 - -13 (PDB: 5LOB)

PDB	External Database	Details
Gly -12	-	expression tag
Ser -11	-	expression tag
His -10	-	expression tag
Met -9	-	expression tag
Ala -8	-	expression tag
Ser -7	-	expression tag
Met -6	-	expression tag
Thr -5	-	expression tag
Gly -4	-	expression tag
Gly -3	-	expression tag
Gln -2	-	expression tag
Gln -1	-	expression tag
Met 0	-	expression tag
Gly 1	-	expression tag
Arg 2	-	expression tag
Gly 3	-	expression tag
Ser 4	-	expression tag
Glu 5	-	expression tag
Phe 6	-	expression tag

D, F: 7 - 82 (UniProt: P60881)
E, G: 108 - 121 (PDB: 5LOB)

PDB	External Database	Details
Gly 122	-	expression tag
Ser 123	-	expression tag
His 124	-	expression tag
Met 125	-	expression tag
Ala 126	-	expression tag
Ser 127	-	expression tag
Met 128	-	expression tag
Thr 129	-	expression tag
Gly 130	-	expression tag
Gly 131	-	expression tag
Gln 132	-	expression tag
Gln 133	-	expression tag
Met 134	-	expression tag
Gly 135	-	expression tag
Arg 136	-	expression tag
Gly 137	-	expression tag
Ser 138	-	expression tag
Glu 139	-	expression tag
Phe 140	-	expression tag

E, G: 141 - 203 (UniProt: P60881)

Contents of the asymmetric unit

Polymers	Number of chains	7
	Total formula weight	99100.6
Non-Polymers*	Number of molecules	25
	Total formula weight	2029.9
All*	Total formula weight	101130.5

*Water molecules are not included.