5LOB

Structure of the Ca2+-bound Rabphilin3A C2B- SNAP25 complex (C2 space group)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane
C	0016020	cellular_component	membrane
D	0000149	molecular_function	SNARE binding
D	0005249	molecular_function	voltage-gated potassium channel activity
D	0017075	molecular_function	syntaxin-1 binding
F	0000149	molecular_function	SNARE binding
F	0005249	molecular_function	voltage-gated potassium channel activity
F	0017075	molecular_function	syntaxin-1 binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue CA A 701

Chain	Residue
A	ASP571
A	ASP577
A	ASP631
A	TYR632
A	ASP633
A	SO4703

---

site_id	AC2
Number of Residues	5
Details	binding site for residue CA A 702

Chain	Residue
A	ASP633
A	ASP639
A	MET570
A	ASP571
A	ASP631

---

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 703

Chain	Residue
A	ASP571
A	ASP577
A	ASP633
A	ILE634
A	CA701

---

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 704

Chain	Residue
A	GLN554
A	ILE558
A	PHE611
A	PHE612
A	SO4705
D	ARG16
D	GLN20

---

site_id	AC5
Number of Residues	4
Details	binding site for residue SO4 A 705

Chain	Residue
A	HIS594
A	PHE612
A	SO4704
D	ARG16

---

site_id	AC6
Number of Residues	2
Details	binding site for residue SO4 A 706

Chain	Residue
A	HIS617
D	GLU55

---

site_id	AC7
Number of Residues	1
Details	binding site for residue GOL A 707

Chain	Residue
A	ASN677

---

site_id	AC8
Number of Residues	3
Details	binding site for residue GOL A 708

Chain	Residue
A	GLU653
A	ARG671
A	TRP672

---

site_id	AC9
Number of Residues	5
Details	binding site for residue CA B 701

Chain	Residue
B	ASP571
B	ASP577
B	ASP631
B	TYR632
B	ASP633

---

site_id	AD1
Number of Residues	5
Details	binding site for residue CA B 702

Chain	Residue
B	MET570
B	ASP571
B	ASP631
B	ASP633
B	ASP639

---

site_id	AD2
Number of Residues	3
Details	binding site for residue SO4 B 703

Chain	Residue
B	THR602
B	LEU603
B	ASN604

---

site_id	AD3
Number of Residues	2
Details	binding site for residue SO4 B 704

Chain	Residue
B	SER637
B	ASN638

---

site_id	AD4
Number of Residues	1
Details	binding site for residue GOL B 705

Chain	Residue
A	ASN677

---

site_id	AD5
Number of Residues	7
Details	binding site for residue CA C 701

Chain	Residue
C	ASP571
C	ASP577
C	ASP631
C	TYR632
C	ASP633
C	CA702
C	SO4703

---

site_id	AD6
Number of Residues	6
Details	binding site for residue CA C 702

Chain	Residue
C	MET570
C	ASP571
C	ASP631
C	ASP633
C	ASP639
C	CA701

---

site_id	AD7
Number of Residues	6
Details	binding site for residue SO4 C 703

Chain	Residue
C	ASP571
C	ASP577
C	TYR632
C	ASP633
C	ILE634
C	CA701

---

site_id	AD8
Number of Residues	2
Details	binding site for residue SO4 E 301

Chain	Residue
E	ASN159
E	MET163

---

site_id	AD9
Number of Residues	5
Details	binding site for residue SO4 F 101

Chain	Residue
F	ASP51
F	GLY54
F	GLU55
G	GLU170
G	SO4301

---

site_id	AE1
Number of Residues	1
Details	binding site for residue GOL F 102

Chain	Residue
F	GOL103

---

site_id	AE2
Number of Residues	1
Details	binding site for residue GOL F 103

Chain	Residue
F	GOL102

---

site_id	AE3
Number of Residues	3
Details	binding site for residue SO4 G 301

Chain	Residue
F	ASP58
F	SO4101
G	THR173

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	399
Details	Domain: {"description":"C2 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00041","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17166855","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CM5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CM6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17166855","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CM5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---