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5LMX

Monomeric RNA polymerase I at 4.9 A resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA-directed RNA polymerase I subunit RPA190polymer1664186677.01UniProt (P10964)
Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)DNA-directed RNA polymerase I 190 kDa polypeptide,A190,DNA-directed RNA polymerase I largest subunit
2B
(B)
DNA-directed RNA polymerase I subunit RPA135polymer1203135910.31UniProt (P22138)
Pfam (PF00562)
Pfam (PF04560)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF06883)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)DNA-directed RNA polymerase I 135 kDa polypeptide,A135,DNA-directed RNA polymerase I polypeptide 2,RNA polymerase I subunit 2
3C
(C)
DNA-directed RNA polymerases I and III subunit RPAC1,DNA-directed RNA polymerases I and III subunit RPAC1polymer38042850.41UniProt (P07703)
Pfam (PF01193)
Pfam (PF01000)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I and III subunit AC1,C37,DNA-directed RNA polymerases I and III 40 kDa polypeptide,C40,RNA polymerases I and III subunit AC1,C37,DNA-directed RNA polymerases I and III 40 kDa polypeptide,C40
4D
(D)
DNA-directed RNA polymerase I subunit RPA14polymer13714599.11UniProt (P50106)
Pfam (PF08203)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)A14,DNA-directed RNA polymerase I 14 kDa polypeptide
5E
(E)
DNA-directed RNA polymerases I, II, and III subunit RPABC1polymer21525117.11UniProt (P20434)
Pfam (PF03871)
Pfam (PF01191)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC1,ABC27,DNA-directed RNA polymerases I,and III 27 kDa polypeptide
6F
(F)
DNA-directed RNA polymerases I, II, and III subunit RPABC2polymer15517931.81UniProt (P20435)
Pfam (PF01192)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC2,ABC23,DNA-directed RNA polymerases I,and III 23 kDa polypeptide
7G
(G)
DNA-directed RNA polymerase I subunit RPA43polymer32636264.91UniProt (P46669)
Pfam (PF03876)
Pfam (PF17875)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)A43,DNA-directed DNA-dependent RNA polymerase 36 kDa polypeptide
8H
(H)
DNA-directed RNA polymerases I, II, and III subunit RPABC3polymer14616525.41UniProt (P20436)
Pfam (PF03870)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC3,ABC14.4,ABC14.5,DNA-directed RNA polymerases I,and III 14.5 kDa polypeptide
9I
(I)
DNA-directed RNA polymerase I subunit RPA12polymer12513676.61UniProt (P32529)
Pfam (PF02150)
Pfam (PF01096)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)A12,A12.2,DNA-directed RNA polymerase I 13.7 kDa polypeptide
10J
(J)
DNA-directed RNA polymerases I, II, and III subunit RPABC5polymer708290.71UniProt (P22139)
Pfam (PF01194)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC5,ABC10-beta,ABC8,DNA-directed RNA polymerases I,and III 8.3 kDa polypeptide
11K
(K)
DNA-directed RNA polymerases I and III subunit RPAC2polymer14216167.91UniProt (P28000)
Pfam (PF13656)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I and III subunit AC2,AC19,DNA-directed RNA polymerases I and III 16 kDa polypeptide,RPA19
12L
(L)
DNA-directed RNA polymerases I, II, and III subunit RPABC4polymer707730.01UniProt (P40422)
Pfam (PF03604)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)RNA polymerases I,II,and III subunit ABC4,ABC10-alpha
13M
(M)
DNA-directed RNA polymerase I subunit RPA49polymer41546721.71UniProt (Q01080)
Pfam (PF06870)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)A49,DNA-directed RNA polymerase I 49 kDa polypeptide
14N
(N)
DNA-directed RNA polymerase I subunit RPA34polymer23326933.51UniProt (P47006)
Pfam (PF08208)
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)A34,DNA-directed DNA-dependent RNA polymerase 34.5 kDa polypeptide,A34.5
15O, P, Q, R, S...
(A, B, I, J, L)
ZINC IONnon-polymer65.46Chemie (ZN)
Sequence modifications
C: 1 - 335 (UniProt: P07703)
C: 336 - 380 (PDB: 5LMX)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains14
Total formula weight595396.3
Non-Polymers*Number of molecules6
Total formula weight392.5
All*Total formula weight595788.8
*Water molecules are not included.

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PDB entries from 2024-11-06

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