5LMK
Structure of phopsho-CDK2-cyclin A in complex with an ATP-competitive inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Cyclin-dependent kinase 2 | polymer | 299 | 34143.5 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 2,p33 protein kinase |
| 2 | B, D | Cyclin-A2 | polymer | 258 | 29624.3 | 2 | UniProt (P20248) Pfam (PF00134) Pfam (PF02984) In PDB | Homo sapiens (Human) | Cyclin-A |
| 3 | C | Cyclin-dependent kinase 2 | polymer | 297 | 33873.2 | 1 | UniProt (P24941) Pfam (PF00069) In PDB | Homo sapiens (Human) | Cell division protein kinase 2,p33 protein kinase |
| 4 | A, C | 4-[4-[3-bromanyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-5-yl]phenyl]benzamide | non-polymer | 499.4 | 2 | Chemie (6ZK) | |||
| 5 | B, D | MONOTHIOGLYCEROL | non-polymer | 108.2 | 2 | Chemie (SGM) | |||
| 6 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 7 | water | water | 18.0 | 230 | Chemie (HOH) |
Sequence modifications
A: 1 - 298 (UniProt: P24941)
C: 1 - 296 (UniProt: P24941)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127265.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1239.3 | |
| All* | Total formula weight | 128504.7 |
