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5LIH

Structure of a peptide-substrate bound to PKCiota core kinase domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Protein kinase C iota typepolymer34940333.42UniProt (P41743)
Pfam (PF00069)
Pfam (PF00433)
Homo sapiens (Human)Atypical protein kinase C-lambda/iota,aPKC-lambda/iota,nPKC-iota
2C, D
(F, G)
PKC Epsilon pseudo substrate sequencepolymer162065.52UniProt (by SIFTS) (Q02156)Homo sapiens
3E, L
(A, B)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
4F, I, M, P
(A, B)
ALUMINUM FLUORIDEnon-polymer84.04Chemie (AF3)
5G, H, K, N, O
(A, B)
MANGANESE (II) IONnon-polymer54.95Chemie (MN)
6J, Q
(A, B)
THIOCYANATE IONnon-polymer58.12Chemie (SCN)
7R, S, T
(A, B, F)
waterwater18.025Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight84797.7
Non-Polymers*Number of molecules13
Total formula weight1581.2
All*Total formula weight86378.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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