5LGS
Crystal structure of mouse CARM1 in complex with ligand P2C3u
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Histone-arginine methyltransferase CARM1 | polymer | 361 | 40850.5 | 4 | UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) | Mus musculus (Mouse) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | E, F, G, H (E, F, G, H) | Polyadenylate-binding protein 1 | polymer | 9 | 940.1 | 4 | UniProt (P11940) | Homo sapiens | Poly(A)-binding protein 1 |
| 3 | I (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | J, L, Q (A, B, D) | 1,2-DIMETHOXYETHANE | non-polymer | 90.1 | 3 | Chemie (DXE) | |||
| 5 | K (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | M (B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 7 | N, O, P (C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 8 | R, S, T, U (E, F, G, H) | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol | non-polymer | 277.3 | 4 | Chemie (QVR) | |||
| 9 | AA, BA, CA, V, W... (F, G, H, A, B...) | water | water | 18.0 | 584 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 130 - 487 (UniProt: Q9WVG6)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 167162.1 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1962.1 | |
| All* | Total formula weight | 169124.2 |
