5LGR
Crystal structure of mouse CARM1 in complex with ligand P1C3u
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Histone-arginine methyltransferase CARM1 | polymer | 361 | 40850.5 | 4 | UniProt (Q9WVG6) Pfam (PF06325) Pfam (PF22528) | Mus musculus (House mouse) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | E, F, G, H (E, F, G, H) | Polyadenylate-binding protein 1 | polymer | 12 | 1273.5 | 4 | UniProt (P11940) | Homo sapiens | Poly(A)-binding protein 1 |
| 3 | I (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | J, K, M, O, Q... (A, B, C, D, E) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 5 | L (A) | 1,2-DIMETHOXYETHANE | non-polymer | 90.1 | 1 | Chemie (DXE) | |||
| 6 | N (B) | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE | non-polymer | 266.3 | 1 | Chemie (PG6) | |||
| 7 | P (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 8 | AA, R, V, Y (H, E, F, G) | (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-[(~{E})-prop-1-enyl]oxolane-3,4-diol | non-polymer | 277.3 | 4 | Chemie (QVR) | |||
| 9 | BA, S, W, X (H, E, F, G) | L-PROLINAMIDE | non-polymer | 114.1 | 4 | Chemie (LPD) | |||
| 10 | U, Z (F, H) | ACETYL GROUP | non-polymer | 44.1 | 2 | Chemie (ACE) | |||
| 11 | CA, DA, EA, FA, GA... (A, B, C, D, E...) | water | water | 18.0 | 765 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 130 - 487 (UniProt: Q9WVG6)
| PDB | External Database | Details |
|---|---|---|
| Gly 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 168495.8 | |
| Non-Polymers* | Number of molecules | 20 |
| Total formula weight | 2584.8 | |
| All* | Total formula weight | 171080.6 |
