5LFR

Crystal structure of glycosylated Myelin-associated glycoprotein (MAG) Ig1-3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Myelin-associated glycoprotein	polymer	317	35014.3	2	UniProt (P20917) Pfam (PF08205) Pfam (PF13927) In PDB	Mus musculus (House Mouse)	Siglec-4a
2	C	alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G10756ZZ)
3	D	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	1	In PDB GlyTouCan (G81315DD)
4	A, B	alpha-D-mannopyranose	non-polymer		180.2	2	Chemie (MAN)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	5	Chemie (NAG)
6	A, B	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
7	A, B	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
8		water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, B: 20 - 325 (UniProt: P20917)

PDB	External Database	Details
Gly 18	-	expression tag
Ser 19	-	expression tag
Ala 326	-	expression tag
Ala 327	-	expression tag
Ala 328	-	expression tag
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70028.7
Branched	Number of molecules	2
	Total formula weight	1659.5
Non-Polymers*	Number of molecules	17
	Total formula weight	2411.1
All*	Total formula weight	74099.3

*Water molecules are not included.