5LCK
A Clickable Covalent ERK 1/2 Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 360 | 41596.9 | 1 | UniProt (P28482) Pfam (PF00069) | Homo sapiens (Human) | MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2 |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F (A) | ~{N}-[2-[[2-[(5-methoxypyridin-3-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]phenyl]propanamide | non-polymer | 432.4 | 1 | Chemie (6TT) | |||
| 4 | G (A) | water | water | 18.0 | 484 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41596.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 816.7 | |
| All* | Total formula weight | 42413.5 |
