5LB4

Apo-structure of humanised RadA-mutant humRadA14

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	DNA repair and recombination protein RadA	polymer	231	25508.1	1	UniProt (O74036) Pfam (PF08423) In PDB	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
2		water	water		18.0	44	Chemie (HOH)

Sequence modifications

A: 108 - 349 (UniProt: O74036)

PDB	External Database	Details
Met 107	-	initiating methionine
Ala 168	Val 168	engineered mutation
Met 169	Ile 169	engineered mutation
Tyr 170	Trp 170	engineered mutation
Ala 201	Tyr 201	engineered mutation
Tyr 202	Val 202	engineered mutation
Gln 213	Leu 213	engineered mutation
Leu 215	Val 215	engineered mutation
Tyr 216	Gln 216	engineered mutation
Ser 219	Glu 219	engineered mutation
Ala 220	Asp 220	engineered mutation
Met 221	Lys 221	engineered mutation
Met 222	Ile 222	engineered mutation
Val 223	Lys 223	engineered mutation
Ser 225	Leu 225	engineered mutation
Tyr 232	Val 232	engineered mutation
Arg 263	Lys 263	engineered mutation
Phe 264	His 264	engineered mutation
Met 267	Asp 267	engineered mutation
Glu 274	Leu 274	engineered mutation
Phe 275	Tyr 275	engineered mutation
-	Arg 288	deletion
-	Pro 289	deletion
-	Asp 290	deletion
-	Ala 291	deletion
-	Phe 292	deletion
-	Phe 293	deletion
-	Gly 294	deletion
-	Asp 295	deletion
-	Pro 296	deletion
-	Thr 297	deletion
-	Arg 298	deletion
-	Pro 299	deletion
Asn 300	Ile 300	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	25508.1
All*	Total formula weight	25508.1

*Water molecules are not included.