5L6E
Crystal structure of the human METTL3-METTL14 complex bound to SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | N6-adenosine-methyltransferase 70 kDa subunit | polymer | 227 | 25886.6 | 1 | UniProt (Q86U44) Pfam (PF05063) In PDB | Homo sapiens (Human) | MT-A70,Methyltransferase-like protein 3 |
| 2 | B | N6-adenosine-methyltransferase subunit METTL14 | polymer | 289 | 33490.1 | 1 | UniProt (Q9HCE5) Pfam (PF05063) In PDB | Homo sapiens (Human) | Methyltransferase-like protein 14 |
| 3 | A | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | B | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | water | water | 18.0 | 358 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59376.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 481.8 | |
| All* | Total formula weight | 59858.5 |
