5L4H
X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with 5-(2-BROMO-ETHYL)-5-ETHYL-PYRIMIDINE-2,4,6-TRIONE (brominated barbiturate)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Proton-gated ion channel | polymer | 317 | 36225.6 | 5 | UniProt (Q7NDN8) Pfam (PF02931) | Gloeobacter violaceus (strain PCC 7421) | GLIC,Ligand-gated ion channel,LGIC |
| 2 | F, G, H, J, K (A, B, C, D, E) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 3 | I (D) | DODECYL-BETA-D-MALTOSIDE | non-polymer | 510.6 | 1 | Chemie (LMT) | |||
| 4 | L (E) | 5-(2-bromoethyl)-5-ethyl-1,3-diazinane-2,4,6-trione | non-polymer | 263.1 | 1 | Chemie (6JW) | |||
| 5 | M, N, O, P, Q (A, B, C, D, E) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 317 (UniProt: Q7NDN8)
| PDB | External Database | Details |
|---|---|---|
| Ser 27 | Cys 69 | conflict |
| Cys 33 | Lys 75 | conflict |
| Cys 246 | Leu 288 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 181128.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 951.0 | |
| All* | Total formula weight | 182079.0 |
