5L3C
Human LSD1/CoREST: LSD1 E379K mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific histone demethylase 1A | polymer | 852 | 93011.5 | 1 | UniProt (O60341) Pfam (PF04433) Pfam (PF01593) | Homo sapiens (Human) | BRAF35-HDAC complex protein BHC110,Flavin-containing amine oxidase domain-containing protein 2 |
| 2 | B (B) | REST corepressor 1 | polymer | 482 | 53102.0 | 1 | UniProt (Q9UKL0) Pfam (PF01448) Pfam (PF00249) Pfam (PF20878) | Homo sapiens (Human) | Protein CoREST |
| 3 | C (A) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 1 | Chemie (FAD) |
Sequence modifications
A: 1 - 852 (UniProt: O60341)
| PDB | External Database | Details |
|---|---|---|
| Lys 379 | Glu 379 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 146113.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 785.5 | |
| All* | Total formula weight | 146899.0 |
