5L30
Factor VIIa in complex with the inhibitor (2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-4,15,17-trimethyl-7-[1-(1H-tetrazol-5-yl)cyclopropyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | H | Coagulation factor VII (Heavy Chain) | polymer | 254 | 28103.3 | 1 | UniProt (P08709) Pfam (PF00089) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
2 | L | Coagulation factor VII (Light Chain) | polymer | 58 | 6387.2 | 1 | UniProt (P08709) Pfam (PF14670) In PDB | Homo sapiens (Human) | Proconvertin,Serum prothrombin conversion accelerator,SPCA |
3 | H | (2R,15R)-2-[(1-aminoisoquinolin-6-yl)amino]-4,15,17-trimethyl-7-[1-(1H-tetrazol-5-yl)cyclopropyl]-13-oxa-4,11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6(21),7,9,16,19-hexaene-3,12-dione | non-polymer | 617.7 | 1 | Chemie (70A) | |||
4 | H | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
5 | H | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
6 | H | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
7 | water | water | 18.0 | 410 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 34490.5 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 1226.2 | |
All* | Total formula weight | 35716.7 |