5L1X

Structure of the Human Metapneumovirus Fusion Protein in the Postfusion Conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	hMPV F2 subunit	polymer	89	10193.5	6	UniProt (H6X1Z1) UniProt (by SIFTS) (Q91F55)	Human metapneumovirus
2	B, D, F, H, J... (B, D, F, H, J...)	hMPV F1 subunit	polymer	387	42056.8	6	UniProt (Q8B9P0) Pfam (PF00523) UniProt (by SIFTS) (Q91F55)	Human metapneumovirus
3	M, N, R (M, N, R)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	3	In PDB GlyTouCan (G21290RB)
4	O, Q (O, Q)	alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		367.3	2	In PDB GlyTouCan (G86851RC)
5	P (P)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	AA, CA, S, U, W... (J, L, B, D, F...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)
7	BA, T, V, X, Y (J, B, D, F, H)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)

Sequence modifications

A, C, E, G, I, K: 19 - 101 (UniProt: H6X1Z1)

PDB	External Database	Details
Lys 102	-	expression tag
Lys 103	-	expression tag
Arg 104	-	expression tag
Lys 105	-	expression tag
Arg 106	-	expression tag
Arg 107	-	expression tag

B, D, F, H, J, L: 112 - 489 (UniProt: Q8B9P0)

PDB	External Database	Details
Ser 490	-	expression tag
Gly 491	-	expression tag
Arg 492	-	expression tag
Glu 493	-	expression tag
Asn 494	-	expression tag
Leu 495	-	expression tag
Tyr 496	-	expression tag
Phe 497	-	expression tag
Gln 498	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	313501.6
Branched	Number of molecules	6
	Total formula weight	2870.7
Non-Polymers*	Number of molecules	11
	Total formula weight	1807.6
All*	Total formula weight	318179.9

*Water molecules are not included.