5L0G
Human metavinculin MVt Q971R, R975D, T978R mutant (residues 959-1134) in complex with PIP2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | Vinculin | polymer | 176 | 19662.7 | 4 | UniProt (P18206) Pfam (PF01044) In PDB | Homo sapiens (Human) | Metavinculin,MV |
2 | B, C | [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | non-polymer | 746.6 | 2 | Chemie (PIO) | |||
3 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 959 - 1134 (UniProt: P18206)
PDB | External Database | Details |
---|---|---|
Arg 971 | Gln 971 | engineered mutation |
Asp 975 | Arg 975 | engineered mutation |
Arg 978 | Thr 978 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 78651.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1493.1 | |
All* | Total formula weight | 80144.1 |