5KZV
Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with 20(S)-hydroxycholesterol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Smoothened | polymer | 127 | 13991.1 | 1 | UniProt (Q98SW5) Pfam (PF01392) | Xenopus laevis (African clawed frog) | |
| 2 | B (A) | (3alpha,8alpha)-cholest-5-ene-3,20-diol | non-polymer | 402.7 | 1 | Chemie (HCD) | |||
| 3 | C (A) | water | water | 18.0 | 235 | Chemie (HOH) |
Sequence modifications
A: 35 - 154 (UniProt: Q98SW5)
| PDB | External Database | Details |
|---|---|---|
| Ala 28 | - | expression tag |
| Met 29 | - | expression tag |
| Ala 30 | - | expression tag |
| Asp 31 | - | expression tag |
| Ile 32 | - | expression tag |
| Gly 33 | - | expression tag |
| Ser 34 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 13991.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 402.7 | |
| All* | Total formula weight | 14393.7 |
