5KZV
Crystal structure of the xenopus Smoothened cysteine-rich domain (CRD) in complex with 20(S)-hydroxycholesterol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0007224 | biological_process | smoothened signaling pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | binding site for residue HCD A 400 |
| Chain | Residue |
| A | ASP68 |
| A | HOH593 |
| A | LEU81 |
| A | TRP82 |
| A | LEU85 |
| A | ASN87 |
| A | GLU133 |
| A | ARG134 |
| A | HOH505 |
| A | HOH562 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27545348","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29804838","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6D35","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Lipidation: {"description":"Cholesterol aspartate ester","evidences":[{"source":"UniProtKB","id":"Q99835","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
