5KZQ
Metabotropic Glutamate Receptor in complex with antagonist (1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-azanyl-3-[[3,4-bis(fluoranyl)phenyl]sulfanylmethyl]-4-oxidanyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Metabotropic glutamate receptor 2 | polymer | 570 | 63310.6 | 1 | UniProt (Q14416) Pfam (PF01094) Pfam (PF07562) In PDB | Homo sapiens (Human) | mGluR2 |
2 | A | (1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-azanyl-3-[[3,4-bis(fluoranyl)phenyl]sulfanylmethyl]-4-oxidanyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid | non-polymer | 359.3 | 1 | Chemie (6YS) | |||
3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
4 | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 1 - 564 (UniProt: Q14416)
PDB | External Database | Details |
---|---|---|
Glu 563 | Trp 563 | conflict |
His 565 | - | expression tag |
His 566 | - | expression tag |
His 567 | - | expression tag |
His 568 | - | expression tag |
His 569 | - | expression tag |
His 570 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 63310.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 580.6 | |
All* | Total formula weight | 63891.1 |