5KZQ
Metabotropic Glutamate Receptor in complex with antagonist (1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-azanyl-3-[[3,4-bis(fluoranyl)phenyl]sulfanylmethyl]-4-oxidanyl-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00979 |
| Number of Residues | 19 |
| Details | G_PROTEIN_RECEP_F3_1 G-protein coupled receptors family 3 signature 1. VaNLLrLFqIPQISyASTS |
| Chain | Residue | Details |
| A | VAL151-SER169 | |
| site_id | PS00980 |
| Number of Residues | 23 |
| Details | G_PROTEIN_RECEP_F3_2 G-protein coupled receptors family 3 signature 2. CCWlCipCqpyeYrl...DefTCadC |
| Chain | Residue | Details |
| A | CYS518-CYS540 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER145 | |
| A | ALA166 | |
| A | TYR216 | |
| A | ASP295 | |
| A | LYS377 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN203 | |
| A | ASN286 | |
| A | ASN338 | |
| A | ASN402 | |
| A | ASN547 | |
