5KYB

Crystal structure of the apo-form of USP7 catalytic domain [V302K] mutant

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ubiquitin carboxyl-terminal hydrolase 7	polymer	351	40617.9	2	UniProt (Q93009) Pfam (PF00443)	Homo sapiens (Human)	Deubiquitinating enzyme 7,Herpesvirus-associated ubiquitin-specific protease,Ubiquitin thioesterase 7,Ubiquitin-specific-processing protease 7
2	C, D (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	E, F (A, B)	water	water		18.0	172	Chemie (HOH)

Sequence modifications

A, B: 208 - 554 (UniProt: Q93009)

PDB	External Database	Details
Gly 204	-	expression tag
Ser 205	-	expression tag
His 206	-	expression tag
Met 207	-	expression tag
Lys 302	Val 286	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	81235.9
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	81420.0

*Water molecules are not included.