5KY8
mouse POFUT1 in complex with O-glucosylated mouse Notch1 EGF12 mutant (D464G) and GDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | GDP-fucose protein O-fucosyltransferase 1 | polymer | 355 | 40457.3 | 1 | UniProt (Q91ZW2) Pfam (PF10250) In PDB | Mus musculus (Mouse) | Peptide-O-fucosyltransferase 1,O-FucT-1 |
| 2 | B | Neurogenic locus notch homolog protein 1 | polymer | 40 | 4375.9 | 1 | UniProt (Q01705) Pfam (PF12661) In PDB | Mus musculus (Mouse) | Notch 1,Motch A,mT14,p300 |
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | A | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | B | beta-D-glucopyranose | non-polymer | 180.2 | 1 | Chemie (BGC) | |||
| 6 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
A: 33 - 384 (UniProt: Q91ZW2)
B: 452 - 491 (UniProt: Q01705)
| PDB | External Database | Details |
|---|---|---|
| Gly 30 | - | expression tag |
| Ala 31 | - | expression tag |
| Pro 32 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 464 | Asp 464 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44833.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 844.6 | |
| All* | Total formula weight | 45677.7 |
