5KX8

Irak4-inhibitor co-structure

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Interleukin-1 receptor-associated kinase 4	polymer	301	33956.2	4	UniProt (Q9NWZ3) Pfam (PF07714) In PDB	Homo sapiens (Human)	IRAK-4,Renal carcinoma antigen NY-REN-64
2	A, B, C, D	~{N}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-5-piperazin-1-yl-pyrazolo[1,5-a]pyrimidine-3-carboxamide	non-polymer		369.4	4	Chemie (6YE)
3		water	water		18.0	27	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	135824.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1477.5
All*	Total formula weight	137302.3

*Water molecules are not included.