5KWA

complete structure of the Mycobacterium tuberculosis proteasomal ATPase Mpa

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Proteasome-associated ATPase	polymer	497	54983.1	2	UniProt (A0A0T9XQP1) Pfam (PF17758) Pfam (PF16450) Pfam (PF00004) UniProt (by SIFTS) (P9WQN5)	Mycobacterium tuberculosis	AAA ATPase forming ring-shaped complexes,Mycobacterial proteasome ATPase
2	C, E (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
3	D, F (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	G, H (A, B)	water	water		18.0	21	Chemie (HOH)

Sequence modifications

A, B: 95 - 602 (UniProt: A0A0T9XQP1)

PDB	External Database	Details
His 92	-	expression tag
His 93	-	expression tag
His 94	-	expression tag
-	Ala 121	deletion
-	Glu 122	deletion
-	Asp 123	deletion
-	Leu 124	deletion
-	Pro 125	deletion
-	Asp 126	deletion
-	Gly 127	deletion
-	Leu 128	deletion
-	Pro 129	deletion
-	Glu 130	deletion
-	Ala 131	deletion
-	Leu 132	deletion
-	Asn 133	deletion
-	Asp 134	deletion
Gly 208	Asp 135	cloning artifact
Gly 209	Thr 136	cloning artifact
Gly 210	Arg 137	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	109966.1
Non-Polymers*	Number of molecules	4
	Total formula weight	903.0
All*	Total formula weight	110869.1

*Water molecules are not included.