5KUY
Influenza hemagglutinin H3 A/Hong Kong/1/1968 in complex with designed inhibitor protein HSB.2A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E | Hemagglutinin HA1 | polymer | 323 | 35506.9 | 3 | UniProt (Q91MA7) Pfam (PF00509) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 2 | B, D, F | Hemagglutinin HA2 | polymer | 177 | 20284.4 | 3 | UniProt (Q91MA7) Pfam (PF00509) In PDB | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 3 | G, H, I | Designed influenza inhibitor HSB.2A | polymer | 97 | 10861.1 | 3 | synthetic construct | ||
| 4 | J, K, L, M, O | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 5 | N | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | A, B, D, E | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 7 | water | water | 18.0 | 470 | Chemie (HOH) |
Sequence modifications
A, C, E: 11 - 329 (UniProt: Q91MA7)
B, D, F: 330 - 505 (UniProt: Q91MA7)
| PDB | External Database | Details |
|---|---|---|
| Ala 7 | - | expression tag |
| Asp 8 | - | expression tag |
| Pro 9 | - | expression tag |
| Gly 10 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 452 | Arg 468 | engineered mutation |
| Ser 506 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 199957.3 | |
| Branched | Number of molecules | 6 |
| Total formula weight | 2708.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 203993.1 |
