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5KQS

Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine and 7-methyl-guanosine-5'-diphosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methyltransferasepolymer26829538.71UniProt (H9A910)
Pfam (PF01728)
UniProt (by SIFTS) (A0A024B7W1)
Zika virus (strain Mr 766) (ZIKV)
2B
(A)
7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATEnon-polymer459.21Chemie (M7G)
3C, D, E, F
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
4G
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
5H
(A)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
6I
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
7J
(A)
waterwater18.0244Chemie (HOH)
Sequence modifications
A: 1 - 266 (UniProt: H9A910)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29538.7
Non-Polymers*Number of molecules8
Total formula weight1380.1
All*Total formula weight30918.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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