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5KQS

Structure of NS5 methyltransferase from Zika virus bound to S-adenosylmethionine and 7-methyl-guanosine-5'-diphosphate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methyltransferasepolymer26829538.71UniProt (H9A910)
UniProt (by SIFTS) (A0A024B7W1)
Zika virus (strain Mr 766) (ZIKV)
2B
(A)
7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATEnon-polymer459.21Chemie (M7G)
3C, D, E, F
(A)
GLYCEROLnon-polymer92.14Chemie (GOL)
4G
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
5H
(A)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
6I
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
7J
(A)
waterwater18.0244Chemie (HOH)
Sequence modifications
A: 1 - 266 (UniProt: H9A910)
PDBExternal DatabaseDetails
Gly -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight29538.7
Non-Polymers*Number of molecules8
Total formula weight1380.1
All*Total formula weight30918.8
*Water molecules are not included.

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PDB entries from 2026-02-25

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