5KQ1

Crystal structure of S. pombe Dcp1/Dcp2 in complex with H. sapiens PNRC2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	mRNA-decapping enzyme subunit 1	polymer	130	15335.5	2	UniProt (Q9P805) Pfam (PF06058)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
2	B, E (C, F)	Proline-rich nuclear receptor coactivator 2	polymer	31	3365.8	2	UniProt (Q9NPJ4) Pfam (PF15365)	Homo sapiens (Human)
3	C, F (B, E)	mRNA decapping complex subunit 2	polymer	249	28945.4	2	UniProt (O13828) Pfam (PF05026) Pfam (PF00293)	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)

Sequence modifications

A, D: 1 - 127 (UniProt: Q9P805)

PDB	External Database	Details
Gly -2	-	expression tag
Glu -1	-	expression tag
Phe 0	-	expression tag

B, E: 1 - 244 (UniProt: O13828)

PDB	External Database	Details
Gly -4	-	expression tag
Gly -3	-	expression tag
Gly -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	95293.2
All*	Total formula weight	95293.2

*Water molecules are not included.