5KMW
TOHO1 Beta lactamase mutant E166A/R274N/R276N -benzyl penicillin complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-lactamase Toho-1 | polymer | 256 | 27503.1 | 1 | UniProt (Q47066) Pfam (PF00144) Pfam (PF00905) Pfam (PF13354) | Escherichia coli | |
| 2 | B, C, G, H, I (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 3 | D (A) | OPEN FORM - PENICILLIN G | non-polymer | 336.4 | 1 | Chemie (PNM) | |||
| 4 | E, F (A) | PENICILLIN G | non-polymer | 334.4 | 2 | Chemie (PNN) | |||
| 5 | J (A) | water | water | 18.0 | 516 | Chemie (HOH) |
Sequence modifications
A: 29 - 284 (UniProt: Q47066)
| PDB | External Database | Details |
|---|---|---|
| Ala 165 | Glu 169 | engineered mutation |
| Asn 271 | Arg 275 | engineered mutation |
| Asn 273 | Arg 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27503.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1485.5 | |
| All* | Total formula weight | 28988.6 |
