5KM6
Human Histidine Triad Nucleotide Binding Protein 1 (hHint1) H112N mutant Ara-A nucleoside phosphoramidate substrate complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Histidine triad nucleotide-binding protein 1 | polymer | 129 | 14072.1 | 1 | UniProt (P49773) Pfam (PF01230) In PDB | Homo sapiens (Human) | Adenosine 5'-monophosphoramidase |
| 2 | A | [(2~{R},3~{S},4~{S},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-~{N}-[2-(1~{H}-indol-3-yl)ethyl]phosphonamidic acid | non-polymer | 489.4 | 1 | Chemie (6US) | |||
| 3 | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 1 - 126 (UniProt: P49773)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Asn 112 | His 112 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14072.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 489.4 | |
| All* | Total formula weight | 14561.6 |
