5KKR
KSR2:MEK1 Complex Bound to the Small Molecule APS-2-79
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B | Kinase suppressor of Ras 2 | polymer | 319 | 36774.6 | 1 | UniProt (Q6VAB6) Pfam (PF07714) In PDB | Homo sapiens (Human) | hKSR2 |
2 | C | Dual specificity mitogen-activated protein kinase kinase 1 | polymer | 395 | 43636.1 | 1 | UniProt (P29678) Pfam (PF00069) In PDB | Oryctolagus cuniculus (Rabbit) | MAPKK 1,ERK activator kinase 1,MAPK/ERK kinase 1,MEK 1 |
3 | B | 6,7-dimethoxy-~{N}-(2-methyl-4-phenoxy-phenyl)quinazolin-4-amine | non-polymer | 387.4 | 1 | Chemie (6U7) |
Sequence modifications
B: 634 - 950 (UniProt: Q6VAB6)
C: 1 - 393 (UniProt: P29678)
PDB | External Database | Details |
---|---|---|
Gly 632 | - | expression tag |
Ala 633 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 80410.6 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 387.4 | |
All* | Total formula weight | 80798.1 |