5KJ8
Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form) - from synchrotron diffraction
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, G (A, G) | Vesicle-associated membrane protein 3 | polymer | 63 | 7231.1 | 2 | UniProt (P63025) Pfam (PF00957) | Rattus norvegicus (Rat) | VAMP-3,Cellubrevin,CEB,Synaptobrevin-3 |
| 2 | B, H (B, H) | Syntaxin-1A | polymer | 66 | 7706.8 | 2 | UniProt (P32851) Pfam (PF05739) | Rattus norvegicus (Rat) | Neuron-specific antigen HPC-1,Synaptotagmin-associated 35 kDa protein,P35A |
| 3 | C, I (C, I) | Synaptosomal-associated protein 25 | polymer | 75 | 8741.7 | 2 | UniProt (P60881) | Rattus norvegicus (Rat) | SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein |
| 4 | D, J (D, J) | Synaptosomal-associated protein 25 | polymer | 64 | 7340.2 | 2 | UniProt (P60881) | Rattus norvegicus (Rat) | SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein |
| 5 | E, F, K (E, F, K) | Synaptotagmin-1 | polymer | 279 | 31988.8 | 3 | UniProt (P21707) Pfam (PF00168) | Rattus norvegicus (Rat) | Synaptotagmin I,SytI,p65 |
| 6 | L, M, N, O, P... (C, E, F, K) | CALCIUM ION | non-polymer | 40.1 | 14 | Chemie (CA) |
Sequence modifications
A, G: 27 - 89 (UniProt: P63025)
| PDB | External Database | Details |
|---|---|---|
| Ala 37 | Asn 24 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 11 |
| Total formula weight | 158006.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 561.1 | |
| All* | Total formula weight | 158567.0 |
