5KIW

p97 ND1-L198W in complex with VIMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transitional endoplasmic reticulum ATPase	polymer	468	52388.9	2	UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862)	Homo sapiens (Human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	C, D (C, D)	Selenoprotein S	polymer	81	9729.3	2	UniProt (Q9BQE4) Pfam (PF06936)	Homo sapiens (Human)	SelS,VCP-interacting membrane protein
3	E, G (A, B)	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
4	F, H (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	I (A)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, B: 1 - 460 (UniProt: P55072)

PDB	External Database	Details
Trp 198	Leu 198	engineered mutation
Arg 461	-	expression tag
Ser 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag

C, D: 49 - 122 (UniProt: Q9BQE4)

PDB	External Database	Details
Met 42	-	initiating methionine
His 43	-	expression tag
His 44	-	expression tag
His 45	-	expression tag
His 46	-	expression tag
His 47	-	expression tag
His 48	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	124236.3
Non-Polymers*	Number of molecules	4
	Total formula weight	1061.0
All*	Total formula weight	125297.3

*Water molecules are not included.