5KHW
Crystal structure of JAK1 in complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Tyrosine-protein kinase JAK1 | polymer | 316 | 36417.5 | 2 | UniProt (P23458) Pfam (PF07714) In PDB | Homo sapiens (Human) | Janus kinase 1,JAK-1 |
| 2 | A, B | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | water | water | 18.0 | 84 | Chemie (HOH) |
Sequence modifications
A, B: 841 - 1154 (UniProt: P23458)
| PDB | External Database | Details |
|---|---|---|
| Gly 839 | - | expression tag |
| Ser 840 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 72834.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 903.0 | |
| All* | Total formula weight | 73737.9 |
