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5KFN

Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 1 mM Mg2+ for 1800s

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase etapolymer43548617.71UniProt (Q9Y253)
Pfam (PF00817)
Pfam (PF21704)
Pfam (PF11799)
Homo sapiens (Human)RAD30 homolog A,Xeroderma pigmentosum variant type protein
2B
(T)
DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3')polymer123637.41Homo sapiens
3C
(P)
DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3')polymer82426.61Homo sapiens
4D, F, G
(A)
MAGNESIUM IONnon-polymer24.33Chemie (MG)
5E
(A)
CALCIUM IONnon-polymer40.11Chemie (CA)
6H, I
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
7J
(A)
2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE)non-polymer507.21Chemie (STP)
8K, L, M
(A, T, P)
waterwater18.0420Chemie (HOH)
Sequence modifications
A: 1 - 432 (UniProt: Q9Y253)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight54681.7
Non-Polymers*Number of molecules7
Total formula weight804.4
All*Total formula weight55486.1
*Water molecules are not included.

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PDB entries from 2025-07-23

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