5KFN

Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: reaction with 1 mM Mg2+ for 1800s

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003684	molecular_function	damaged DNA binding
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	binding site for residue MG A 501

Chain	Residue
A	ASP13
A	ASP115
A	GLU116
A	CA502
A	MG503
A	MG504
A	STP507
A	HOH605
P	DT8

---

site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 502

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
A	MG504
A	STP507

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MG A 503

Chain	Residue
A	ASP13
A	MET14
A	ASP115
A	MG501
A	MG504
A	STP507

---

site_id	AC4
Number of Residues	8
Details	binding site for residue MG A 504

Chain	Residue
A	ASP13
A	GLU116
A	MG501
A	CA502
A	MG503
A	STP507
A	HOH605
A	HOH640

---

site_id	AC5
Number of Residues	10
Details	binding site for residue GOL A 505

Chain	Residue
A	ARG24
A	PRO244
A	PHE247
A	SER248
A	GLY276
A	GLU277
A	HOH699
A	HOH715
A	HOH722
A	HOH763

---

site_id	AC6
Number of Residues	9
Details	binding site for residue GOL A 506

Chain	Residue
A	ASN26
A	PRO27
A	HIS28
A	GLY271
A	GLU273
A	TYR274
A	GLU277
A	HOH614
A	HOH626

---

site_id	AC7
Number of Residues	29
Details	binding site for residue STP A 507

Chain	Residue
A	ASP13
A	MET14
A	ASP15
A	CYS16
A	PHE17
A	PHE18
A	ILE48
A	ALA49
A	TYR52
A	ARG55
A	ARG61
A	ASP115
A	GLU116
A	LYS231
A	MG501
A	CA502
A	MG503
A	MG504
A	HOH605
A	HOH639
A	HOH640
A	HOH692
A	HOH733
A	HOH771
P	DT8
P	HOH107
T	DT3
T	DT4
T	DA5

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197, ECO:0007744|PDB:5KFO

Chain	Residue	Details
A	ASP13
A	MET14
A	ASP115
A	GLU116

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:27284197

Chain	Residue	Details
A	ARG61

---