5KCX
Pim-1 kinase in Complex with a Selective N-substituted 7-azaindole Inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase pim-1 | polymer | 291 | 33618.1 | 1 | UniProt (P11309) Pfam (PF00069) In PDB | Homo sapiens (Human) | |
| 2 | A | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | A | 4-chloranyl-1-methyl-2-[4-(4-methylpiperazin-1-yl)phenyl]pyrrolo[2,3-b]pyridine-6-carboxamide | non-polymer | 383.9 | 1 | Chemie (6S3) | |||
| 5 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A: 29 - 313 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| His 314 | - | expression tag |
| His 315 | - | expression tag |
| His 316 | - | expression tag |
| His 317 | - | expression tag |
| His 318 | - | expression tag |
| His 319 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33618.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 512.0 | |
| All* | Total formula weight | 34130.1 |
