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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

5KCR

Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Avilamycin C, mRNA and P-site tRNA at 3.6A resolution

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
11A23S Ribosomal RNApolymer2904941813.61GenBank (802133627)Escherichia coli (strain K12)
21B5S Ribosomal RNApolymer12038790.11GenBank (991970073)Escherichia coli (strain K12)
31D50S ribosomal protein L2polymer27329923.61UniProt (P60422)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Escherichia coli (strain K12)
41E50S ribosomal protein L3polymer20922291.61UniProt (P60438)
Pfam (PF00297)
In PDB		Escherichia coli (strain K12)
51F50S ribosomal protein L4polymer20122121.61UniProt (P60723)
Pfam (PF00573)
In PDB		Escherichia coli (strain K12)
61G50S ribosomal protein L5polymer17920333.61UniProt (P62399)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Escherichia coli (strain K12)
71H50S ribosomal protein L6polymer17718932.81UniProt (P0AG55)
Pfam (PF00347)
In PDB		Escherichia coli (strain K12)
81I50S ribosomal protein L9polymer14915789.01UniProt (P0A7R1)
Pfam (PF01281)
Pfam (PF03948)
In PDB		Escherichia coli (strain K12)
91J50S ribosomal protein L10polymer16517736.61UniProt (P0A7J3)
Pfam (PF00466)
In PDB		Escherichia coli (strain K12)50S ribosomal protein L8
101K50S ribosomal protein L11polymer14214894.41UniProt (P0A7J7)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Escherichia coli (strain K12)
111N50S ribosomal protein L13polymer14216050.61UniProt (P0AA10)
Pfam (PF00572)
In PDB		Escherichia coli (strain K12)
121O50S ribosomal protein L14polymer12313565.11UniProt (P0ADY3)
Pfam (PF00238)
In PDB		Escherichia coli (strain K12)
131P50S ribosomal protein L15polymer14415008.51UniProt (P02413)
Pfam (PF00828)
In PDB		Escherichia coli (strain K12)
141Q50S ribosomal protein L16polymer13615312.31UniProt (P0ADY7)
Pfam (PF00252)
In PDB		Escherichia coli (strain K12)
151R50S ribosomal protein L17polymer12714393.71UniProt (P0AG44)
Pfam (PF01196)
In PDB		Escherichia coli (strain K12)
161S50S ribosomal protein L18polymer11712794.71UniProt (P0C018)
Pfam (PF00861)
In PDB		Escherichia coli (strain K12)
171T50S ribosomal protein L19polymer11513159.31UniProt (P0A7K6)
Pfam (PF01245)
In PDB		Escherichia coli (strain K12)
181U50S ribosomal protein L20polymer11813528.01UniProt (P0A7L3)
Pfam (PF00453)
In PDB		Escherichia coli (strain K12)
191V50S ribosomal protein L21polymer10311586.41UniProt (P0AG48)
Pfam (PF00829)
In PDB		Escherichia coli (strain K12)
201W50S ribosomal protein L22polymer11012253.41UniProt (P61175)
Pfam (PF00237)
In PDB		Escherichia coli (strain K12)
211X50S ribosomal protein L23polymer10011222.21UniProt (P0ADZ0)
Pfam (PF00276)
In PDB		Escherichia coli (strain K12)
221Y50S ribosomal protein L24polymer10411339.31UniProt (P60624)
Pfam (PF00467)
Pfam (PF17136)
In PDB		Escherichia coli (strain K12)
231Z50S ribosomal protein L25polymer9410713.51UniProt (P68919)
Pfam (PF01386)
In PDB		Escherichia coli (strain K12)
241050S ribosomal protein L27polymer859146.51UniProt (P0A7L8)
Pfam (PF01016)
In PDB		Escherichia coli (strain K12)
251150S ribosomal protein L28polymer789027.61UniProt (P0A7M2)
Pfam (PF00830)
In PDB		Escherichia coli (strain K12)
261250S ribosomal protein L29polymer637286.51UniProt (P0A7M6)
Pfam (PF00831)
In PDB		Escherichia coli (strain K12)
271350S ribosomal protein L30polymer596554.81UniProt (P0AG51)
Pfam (PF00327)
In PDB		Escherichia coli (strain K12)
281550S ribosomal protein L32polymer576463.41UniProt (P0A7N4)
Pfam (PF01783)
In PDB		Escherichia coli (strain K12)
291650S ribosomal protein L33polymer556388.61UniProt (P0A7N9)
Pfam (PF00471)
In PDB		Escherichia coli (strain K12)
301750S ribosomal protein L34polymer465397.51UniProt (P0A7P5)
Pfam (PF00468)
In PDB		Escherichia coli (strain K12)
311850S ribosomal protein L35polymer657313.01UniProt (P0A7Q1)
Pfam (PF01632)
In PDB		Escherichia coli (strain K12)Ribosomal protein A
321950S ribosomal protein L36polymer384377.41UniProt (P0A7Q6)
Pfam (PF00444)
In PDB		Escherichia coli (strain K12)Ribosomal protein B
331a16S Ribosomal RNApolymer1539498725.41GenBank (731469900)Escherichia coli (strain K12)
341b30S ribosomal protein S2polymer24126781.71UniProt (P0A7V0)
Pfam (PF00318)
In PDB		Escherichia coli (strain K12)
351c30S ribosomal protein S3polymer23326031.31UniProt (P0A7V3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Escherichia coli (strain K12)
361d30S ribosomal protein S4polymer20623514.21UniProt (P0A7V8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Escherichia coli (strain K12)
371e30S ribosomal protein S5polymer16717629.41UniProt (P0A7W1)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Escherichia coli (strain K12)
381f30S ribosomal protein S6polymer13515727.51UniProt (P02358)
Pfam (PF01250)
In PDB		Escherichia coli (strain K12)
391g30S ribosomal protein S7polymer17920055.21UniProt (P02359)
Pfam (PF00177)
In PDB		Escherichia coli (strain K12)
401h30S ribosomal protein S8polymer13014146.61UniProt (P0A7W7)
Pfam (PF00410)
In PDB		Escherichia coli (strain K12)
411i30S ribosomal protein S9polymer13014886.31UniProt (P0A7X3)
Pfam (PF00380)
In PDB		Escherichia coli (strain K12)
421j30S ribosomal protein S10polymer10311755.61UniProt (P0A7R5)
Pfam (PF00338)
In PDB		Escherichia coli (strain K12)
431k30S ribosomal protein S11polymer12913871.01UniProt (P0A7R9)
Pfam (PF00411)
In PDB		Escherichia coli (strain K12)
441l30S ribosomal protein S12polymer12413768.21UniProt (P0A7S3)
Pfam (PF00164)
In PDB		Escherichia coli (strain K12)
451m30S ribosomal protein S13polymer11813128.51UniProt (P0A7S9)
Pfam (PF00416)
In PDB		Escherichia coli (strain K12)
461n30S ribosomal protein S14polymer10111606.61UniProt (P0AG59)
Pfam (PF00253)
In PDB		Escherichia coli (strain K12)
471o30S ribosomal protein S15polymer8910290.81UniProt (P0ADZ4)
Pfam (PF00312)
In PDB		Escherichia coli (strain K12)
481p30S ribosomal protein S16polymer829207.61UniProt (P0A7T3)
Pfam (PF00886)
In PDB		Escherichia coli (strain K12)
491q30S ribosomal protein S17polymer849724.51UniProt (P0AG63)
Pfam (PF00366)
In PDB		Escherichia coli (strain K12)
501r30S ribosomal protein S18polymer759005.51UniProt (P0A7T7)
Pfam (PF01084)
In PDB		Escherichia coli (strain K12)
511s30S ribosomal protein S19polymer9210455.41UniProt (P0A7U3)
Pfam (PF00203)
In PDB		Escherichia coli (strain K12)
521t30S ribosomal protein S20polymer879708.51UniProt (P0A7U7)
Pfam (PF01649)
In PDB		Escherichia coli (strain K12)
531u30S ribosomal protein S21polymer718524.01UniProt (P68679)
Pfam (PF01165)
In PDB		Escherichia coli (strain K12)
541vmRNApolymer92832.71Synthetic
551xP-site tRNApolymer8728094.61GenBank (1016298593)Escherichia coli (strain K12)
561A(2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name)non-polymer1406.31Chemie (6UQ)
5719ZINC IONnon-polymer65.41Chemie (ZN)
Sequence modifications
1A: 1 - 2904 (GenBank: 802133627)
PDBExternal DatabaseDetails
G 1847A 2723642conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains55
Total formula weight2194979.6
Non-Polymers*Number of molecules2
Total formula weight1471.7
All*Total formula weight2196451.2
*Water molecules are not included.

218853

PDB entries from 2024-04-24

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