5KB5

Crystal structure of the adenosine kinase from Mus musculus in complex with adenosine and adenosine-diphosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adenosine kinase	polymer	363	40632.9	1	UniProt (P55264) Pfam (PF00294)	Mus musculus (Mouse)	AK,Adenosine 5'-phosphotransferase
2	B (A)	ADENOSINE	non-polymer		267.2	1	Chemie (ADN)
3	C (A)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
4	D (A)	POTASSIUM ION	non-polymer		39.1	1	Chemie (K)
5	E (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
6	F, G (A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
7	H, I (A)	TETRAETHYLENE GLYCOL	non-polymer		194.2	2	Chemie (PG4)
8	J, K (A)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
9	L (A)	water	water		18.0	131	Chemie (HOH)

Sequence modifications

A: 20 - 361 (UniProt: P55264)

PDB	External Database	Details
Met -1	-	initiating methionine
Gly 0	-	expression tag
His 1	-	expression tag
His 2	-	expression tag
His 3	-	expression tag
His 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
Glu 7	-	expression tag
Asn 8	-	expression tag
Leu 9	-	expression tag
Tyr 10	-	expression tag
Phe 11	-	expression tag
Gln 12	-	expression tag
Gly 13	-	expression tag
His 14	-	expression tag
Met 15	-	expression tag
Ala 16	-	expression tag
Ser 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	40632.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1396.0
All*	Total formula weight	42028.9

*Water molecules are not included.