5K9Q
Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.a.26 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, M, O... (A, C, E, M, O...) | Hemagglutinin HA1 | polymer | 320 | 35225.6 | 6 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus | |
| 2 | B, D, F, N, P... (B, D, F, N, P...) | Hemagglutinin HA2 | polymer | 170 | 19728.7 | 6 | UniProt (Q91MA7) Pfam (PF00509) | Influenza A virus (strain A/Hong Kong/1/1968 H3N2) | |
| 3 | G, H, J, S, U... (G, H, J, S, U...) | 16.a.26 Heavy chain | polymer | 231 | 24567.6 | 6 | Homo sapiens | ||
| 4 | I, K, L, T, V... (I, K, L, T, V...) | 16.a.26 Light chain | polymer | 214 | 23585.2 | 6 | Homo sapiens (Human) | ||
| 5 | AA, AB, BA, BB, CA... (A, O, P, Q, B...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 36 | Chemie (NAG) | |||
| 6 | AC, BC, CC, DC, EC... (S, T, U, V, X...) | water | water | 18.0 | 1669 | Chemie (HOH) |
Sequence modifications
A, C, E, M, O, Q: 8 - 327 (UniProt: Q91MA7)
| PDB | External Database | Details |
|---|---|---|
| Glu 218 | Gly 234 | conflict |
| Ala 327 | Gln 343 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 618642.8 | |
| Non-Polymers* | Number of molecules | 36 |
| Total formula weight | 7963.5 | |
| All* | Total formula weight | 626606.3 |
