5K70
Sidekick-2 immunoglobulin domains 1-4 H18R/N22S mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein sidekick-2 | polymer | 384 | 42381.2 | 4 | UniProt (Q6V4S5) Pfam (PF13927) Pfam (PF07679) | Mus musculus (Mouse) | |
| 2 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 3 | F, G, H (F, G, H) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 3 | In PDB GlyTouCan (G86851RC) | |||
| 4 | I, P, U (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 5 | J, K, L, M, N... (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 14 | Chemie (PO4) | |||
| 6 | AA, BA, CA, Z (B, C, D, A) | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -2 - 379 (UniProt: Q6V4S5)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg 18 | His 42 | engineered mutation |
| Ser 22 | Asn 46 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 169524.8 | |
| Branched | Number of molecules | 4 |
| Total formula weight | 1672.6 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1993.2 | |
| All* | Total formula weight | 173190.6 |
